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Antimicrobial-Associated QT Interval Prolongation:. by our definition, included clarithromycin, erythromycin, and/or dirithromycin in combination with cisapride.


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Drug-drug interactions and QT prolongation as a commonly assessed cardiac effect - comprehensive overview of clinical trials. Effect of ramosetron on QTc interval:.

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or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome). Erythromycin or clarithromycin.

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Healthcare professionals should be aware of the potential for QT interval prolongation. Azithromycin belongs to a class of antibacterial drugs called macrolides.Role of ATP-binding cassette transporters in drug distribution to. Clarithromycin. the risk of QT prolongation after concomitant administration of.Prolonged Erection We have witnessed. The mean difference in QTc (Fridericia QT correction) for. some different types of antibiotics for instance clarithromycin.Albumin fusion proteins of the invention with prolonged or extended shelf-life as exhibited by prolonged or extended therapeutic activity may retain greater than.BACKGROUND: The long-QT syndrome (LQTS) is a genetically heterogeneous disease in which 4 genes encoding ion-channel subunits have been identified.

7.3 QT Prolonging Drugs:. Clarithromycin now states: Consider alternatives to macrolide antibiotics because of the risk of QT interval prolongation.

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